Omicron better at invading young noses than other variants

The finding is the result of a recent test-tube experiments mixing the virus with nasal cells from 23 healthy children and 15 healthy adults

Reuters
Published : 3 August 2022, 03:36 AM
Updated : 3 August 2022, 03:36 AM

The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that has yet to be certified by peer review.

CHILDRENS' NOSES DEFEND LESS WELL AGAINST OMICRON

The omicron variant may be more efficient at infecting children through the nose than previous versions of the coronavirus, a small study suggests.

Earlier in the pandemic, children's noses had been less welcoming to the virus that causes COVID-19 than adults' noses. Studies of the original SARS-CoV-2 and some of its variants found the virus was met with stronger immune responses in the cells lining young noses than in adults' nasal-lining cells, and it was less efficient at making copies of itself in children's noses.

But recent test-tube experiments mixing the virus with nasal cells from 23 healthy children and 15 healthy adults found the antiviral defenses in kids' noses "was markedly less pronounced in the case of omicron," researchers reported on Monday in PLOS Biology.

They also report that omicron reproduced itself more efficiently in childrens' nasal-lining cells compared to both Delta and the original virus.

"These data are consistent with the increased number of pediatric infections observed during the omicron wave," the researchers wrote, while calling for additional studies.

SMELL PROBLEMS MAY PREDICT MEMORY PROBLEMS AFTER COVID-19

Severity of smell dysfunction after infection with the coronavirus may be a better predictor of long-term cognitive impairment than overall severity of COVID-19, according to an Argentinian study.

Researchers studied a random sample of 766 people over age 60, roughly 90% of whom had been infected with the virus. Physical, cognitive and neuropsychiatric tests performed three-to-six months after infection showed some degree of memory impairment in two-thirds of the infected participants.

After taking individuals' other risk factors into account, severity of loss of smell, known as anosmia, "but not clinical status, significantly (predicted) cognitive impairment," the researchers reported on Sunday at the Alzheimer's Association International Conference 2022, held online and in San Diego.

"The more insight we have into what causes or at least predicts who will experience the significant long-term cognitive impact of COVID-19 infection, the better we can track it and begin to develop methods to prevent it," study leader Gabriela Gonzalez-Aleman of Pontificia Universidad Catolica Argentina in Buenos Aires said in a statement.

Toufique Imrose Khalidi
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