The Paris St-Germain player was substituted after tweaking his groin as he shot at goal with seven minutes gone in the international match at Milton Keynes in England.
However, doctor Rodrigo Lasmar told reporters that while a scan was needed to comfirm the exact diagnosis he did not think the injury to Neymar's adductor muscle would keep him out long.
"He came off complaining of pain," said Lasmar. "He felt a discomfort, he will need a bit more time to evaluate it and take a scan, but in principle it is not a serious injury."
Neymar's injury was not the only concern for PSG on Tuesday with his club strike partner Kylian Mbappe also withdrawn before halftime in France's 1-0 friendly win against Uruguay.
The forward fell awkwardly on his right shoulder after a challenge by Uruguay goalkeeper Marin Campana.