NEW YORK (Reuters) - Actor Heath Ledger died of an accidental overdose of six prescription drugs, with a combination of painkillers, tranquilizers and sleeping aids found in his system, officials said on Wednesday.
"We have concluded that the manner of death is accident, resulting from the abuse of prescription medications," the New York City Medical Examiner's Office said in a statement.
"Mr. Heath Ledger died as the result of acute intoxication by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam and doxylamine," the statement said.
Australian-born Ledger, 28, renowned for his role as a conflicted gay cowboy in the 2005 movie "Brokeback Mountain," was found dead in his Manhattan apartment on January 22, naked and with several prescription drugs nearby.
His death shocked film fans and fellow actors around the world and added his name to the list of movie stars who died young, like Marilyn Monroe and James Dean.
Kim Ledger, the actor's father, said the family was humbled by the outpouring of support from fans around the world and asked to be allowed to grieve privately.
"Today's results put an end to speculation, but our son's beautiful spirit and enduring memory will forever remain in our hearts," he said in a statement.
"While no medications were taken in excess, we learned today the combination of doctor-prescribed drugs proved lethal for our boy."
SIX PRESCRIPTION DRUGS
The painkillers oxycodone and hydrocodone are opiates, which are dangerous when combined with anti-anxiety medicines like diazepam, alprazolam and temazepam. According to a Drug Enforcement Administration Web site, oxycodone is often abused and an acute overdose can cause respiratory arrest and death.
Diazepam is sold under the brand name Valium and alprazolam is sold under the name Xanax. Temazepam is also used as a sleep aid and sold under the name Restoril. Doxylamine, a sleep aid and antihistamine, is an active ingredient in a number of over-the-counter medications, including NyQuil.
Ledger had said in recent interviews he was having trouble sleeping during the filming of the latest Batman film "The Dark Knight" in which he plays The Joker, a homicidal maniac. The film is due out in July.
Andrew Kolodny, a psychiatrist at Maimonides Medical Center in Brooklyn, said, "If someone has an overdose death with that kind of toxicology report, it's usually an indication that they were either doctor-shopping or purchasing medications either on the street or on the Internet."
The handsome star had been romantically linked with a number of actresses and models, periodically spotted in fancy clubs and night spots around New York.
He recently had been in a committed relationship with actress Michelle Williams, the mother of their 2-year-old daughter, Matilda, but the couple split in September. Some reports said Ledger was having difficulty with the breakup.
The couple met during the filming of "Brokeback Mountain," for which Ledger received an Oscar nomination.
Other film credits included "The Patriot" in 2000, "Monster's Ball" in 2001 and "I'm Not There" in 2007.
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