The attack injures 21 and damages infrastructure facilities, local officials report
"The virus doesn't understand administrative boundaries or different political stripes," he told a joint news conference with Health Minister Salvador Illa.
Spain's regions have a high degree of autonomy and are largely responsible for responding to the pandemic but restrictions on freedom of movement, like curfews, require the national government's intervention.
The central government is actually also in favour of curfews, but postponed a decision after the Madrid region and the Basque country opposed such a move on Thursday.
Prime Minister Pedro Sanchez is due to make a televised address to the nation at around 1100 GMT to speak about the pandemic.