The American football star and actor was acquitted in a sensational 1995 trial of murdering his former wife
Last week, Trudeau met US President Joe Biden and attended the Summit of the Americas in California, where leaders from the region gathered to discuss issues impacting those countries, including immigration.
"I've tested positive for COVID-19. I'll be following public health guidelines and isolating. I feel okay, but that's because I got my shots," Trudeau, who is now in Ottawa, said in a tweet.
Trudeau, 50, previously tested positive for COVID in January.