British actor Tom Holland, who plays the web-slinging hero, showed up at the premiere accompanied by an actor in full Spider-Man costume who was lying on the bonnet of a car and performing back flips for the crowd.
"I think for me I've realised the responsibility of being a role model for young kids everywhere," Holland told reporters, adding that the character's motto that "with great power comes great responsibility", resonated with him.
The film is the first time that Spider-Man, one of Disney-owned Marvel's most popular characters, is the lead in a film set in the Marvel Cinematic Universe.
"Now we have the first time Spider-Man in the Marvel Universe where he belongs," he stated at the premiere, adding "I sort of am still pinching myself. I can't believe it. I can't believe we're premiering the movie tonight and I can't wait for people to see it."
The film sees "Iron Man" actor Robert Downey Jr, another staple of the Marvel Cinematic Universe, who has featured in several of the series' films, taking a co-starring role alongside Holland.
The film is released in European cinemas on July 5, and July 7 in the United States.