He is playing his first tournament since suffering serious injuries in a car accident in December 2022 that kept him out of last year's IPL as well as the 50-overs World Cup in India
Three changes have been made to the squad from the last series against New Zealand.
World Cup hero Shakib Al Hasan will lead the side in Chattogram after sitting out the ODI series against Sri Lanka.
He replaces left-arm seamer Mustafizur Rahman, who has been rested for the game against the Afghans.
All-rounder Mosaddek Hossain also features in the squad as talismanic opener Tamim Iqbal is given a breather after his recent struggle for runs.