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It turns out that a specific chemical in your toothpaste is responsible for that nasty taste.
According to researchers from the American Chemical Society, a non-profit organisation, you are actually experiencing a two-pronged attack on your taste buds.
It results from a chemical called sodium lauryl sulfate found in everything from toilet cleaning products to yes, your toothpaste.
When this taste-bud-warping chemical comes in contact with vitamin C in Orange juice, it gives you a nasty taste, researchers said.