Rizwan and Irfan both suffered hamstring injuries in the third match in Rawalpindi, where a second-string New Zealand side won by seven wickets to level the five-match series 1-1
Australia, who were beaten inside four days in the first test in Dhaka, will resume on 225 for two, still 80 behind the hosts' first innings total of 305 at the Zahur Ahmed Chowdhury Stadium.
David Warner will resume on 88 with Peter Handscomb on 69, the blossoming third wicket partnership already worth 127 runs.